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mut s mgrb truncated strain backgrounds  (ATCC)
98
ATCC mut s mgrb truncated strain backgrounds
Transcriptomic analysis <t>of</t> <t>Mut-S</t> in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the <t>mgrB,</t> phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.
Mut S Mgrb Truncated Strain Backgrounds, supplied by ATCC, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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strain background  (ATCC)
95
ATCC strain background
Transcriptomic analysis <t>of</t> <t>Mut-S</t> in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the <t>mgrB,</t> phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.
Strain Background, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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strain background - by Bioz Stars, 2026-06
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mouse strain cd1 swiss genetic background  (Janvier Labs)
86
Janvier Labs mouse strain cd1 swiss genetic background
Transcriptomic analysis <t>of</t> <t>Mut-S</t> in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the <t>mgrB,</t> phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.
Mouse Strain Cd1 Swiss Genetic Background, supplied by Janvier Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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c57bl 6j strain background  (Jackson Laboratory)
86
Jackson Laboratory c57bl 6j strain background
Transcriptomic analysis <t>of</t> <t>Mut-S</t> in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the <t>mgrB,</t> phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.
C57bl 6j Strain Background, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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strain background  (TaKaRa)
96
TaKaRa strain background
Transcriptomic analysis <t>of</t> <t>Mut-S</t> in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the <t>mgrB,</t> phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.
Strain Background, supplied by TaKaRa, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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background strain c57bl 6j  (Jackson Laboratory)
86
Jackson Laboratory background strain c57bl 6j
Transcriptomic analysis <t>of</t> <t>Mut-S</t> in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the <t>mgrB,</t> phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.
Background Strain C57bl 6j, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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background strain dba 2j mice control  (Jackson Laboratory)
86
Jackson Laboratory background strain dba 2j mice control
Study design outlining treatment <t>of</t> <t>DBA/2J</t> (control), D2. mdx vehicle, and D2. mdx NDC□1171 groups (n = 9 per group). Mice received oral gavage from 6 to 14 weeks of age. Ultrasound transducer icons denote timepoints at which transthoracic echocardiography wa performed (baseline: 6, midpoint: 11, endpoint: 14, and post-behavior: 16 weeks of age; n□=□5–6 per group). Behavioral testing icon represents the functional behavior testing (treadmill exhaustion and four□limb grip strength) conducted at week 15. Mice were euthanized at week 17 and cardiac tissue was collected for histological evaluation.
Background Strain Dba 2j Mice Control, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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strain background mus musculus b6 dba  (Jackson Laboratory)
86
Jackson Laboratory strain background mus musculus b6 dba
Study design outlining treatment <t>of</t> <t>DBA/2J</t> (control), D2. mdx vehicle, and D2. mdx NDC□1171 groups (n = 9 per group). Mice received oral gavage from 6 to 14 weeks of age. Ultrasound transducer icons denote timepoints at which transthoracic echocardiography wa performed (baseline: 6, midpoint: 11, endpoint: 14, and post-behavior: 16 weeks of age; n□=□5–6 per group). Behavioral testing icon represents the functional behavior testing (treadmill exhaustion and four□limb grip strength) conducted at week 15. Mice were euthanized at week 17 and cardiac tissue was collected for histological evaluation.
Strain Background Mus Musculus B6 Dba, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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background strain wistar rats crlj wi  (Jackson Laboratory)
86
Jackson Laboratory background strain wistar rats crlj wi
Study design outlining treatment <t>of</t> <t>DBA/2J</t> (control), D2. mdx vehicle, and D2. mdx NDC□1171 groups (n = 9 per group). Mice received oral gavage from 6 to 14 weeks of age. Ultrasound transducer icons denote timepoints at which transthoracic echocardiography wa performed (baseline: 6, midpoint: 11, endpoint: 14, and post-behavior: 16 weeks of age; n□=□5–6 per group). Behavioral testing icon represents the functional behavior testing (treadmill exhaustion and four□limb grip strength) conducted at week 15. Mice were euthanized at week 17 and cardiac tissue was collected for histological evaluation.
Background Strain Wistar Rats Crlj Wi, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Transcriptomic analysis of Mut-S in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the mgrB, phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.

Journal: Nucleic Acids Research

Article Title: PhoP-regulated VirK acts as an accessory factor to maintain virulence in polymyxin-resistant Klebsiella pneumoniae

doi: 10.1093/nar/gkag290

Figure Lengend Snippet: Transcriptomic analysis of Mut-S in comparison to Kpn2146 strains. ( A ) Volcano map displaying the upregulated (red dots) and downregulated (yellow dots) genes between the Mut-S group and the control group. ( B ) Changes in the relative expression of the mgrB, phoP , and virK genes in the Mut-S strain compared with those in the WT strain. ( C )Changes in the virK gene expression in the Mut-S strain after supplementation with the mgrB gene. ( D ) Changes in phoP and virK gene expressions after phoP gene knockdown in the Mut-S strain. ( E ) Changes in the mgrB and virK gene expressions after the mgrB gene was complemented in the phoP knockout strain in Mut-S. ( F ) Changes in the phoP and virK gene expressions after the phoP gene was supplemented in the phoP knockout strains in Mut-S. * P < 0.05, ** P < 0.01, *** P < 0.001, and **** P < 0.0001.

Article Snippet: The effects of virK on bacterial pathogenicity were further evaluated in a mouse systemic infection model using virK mutants and complemented strains under K. pneumoniae ATCC BAA2146 (wild type) or Mut-S ( mgrB truncated strain) backgrounds.

Techniques: Comparison, Control, Expressing, Gene Expression, Knockdown, Knock-Out

Study design outlining treatment of DBA/2J (control), D2. mdx vehicle, and D2. mdx NDC□1171 groups (n = 9 per group). Mice received oral gavage from 6 to 14 weeks of age. Ultrasound transducer icons denote timepoints at which transthoracic echocardiography wa performed (baseline: 6, midpoint: 11, endpoint: 14, and post-behavior: 16 weeks of age; n□=□5–6 per group). Behavioral testing icon represents the functional behavior testing (treadmill exhaustion and four□limb grip strength) conducted at week 15. Mice were euthanized at week 17 and cardiac tissue was collected for histological evaluation.

Journal: bioRxiv

Article Title: Positive allosteric modulator of SERCA pump NDC-1171 attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy

doi: 10.64898/2026.03.05.709950

Figure Lengend Snippet: Study design outlining treatment of DBA/2J (control), D2. mdx vehicle, and D2. mdx NDC□1171 groups (n = 9 per group). Mice received oral gavage from 6 to 14 weeks of age. Ultrasound transducer icons denote timepoints at which transthoracic echocardiography wa performed (baseline: 6, midpoint: 11, endpoint: 14, and post-behavior: 16 weeks of age; n□=□5–6 per group). Behavioral testing icon represents the functional behavior testing (treadmill exhaustion and four□limb grip strength) conducted at week 15. Mice were euthanized at week 17 and cardiac tissue was collected for histological evaluation.

Article Snippet: Male D2. mdx mice (n=18, strain #013141, D2.B10-Dmdmdx/J) and its background strain DBA/2J mice (Control) were obtained from Jackson Laboratory at 4 weeks of age (n=9).

Techniques: Control, Functional Assay

D2. mdx vehicle-treated mice (Vehicle) had impairments when compared to DBA/2J vehicle-treated (Control) in both (A) Four-limb grip strength test and (B) Treadmill exhaustion test. D2. mdx mice treated with NDC-1171 did not improve in either behavior assessments. * p <0.05, ** p <0.01, and *** p <0.001.

Journal: bioRxiv

Article Title: Positive allosteric modulator of SERCA pump NDC-1171 attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy

doi: 10.64898/2026.03.05.709950

Figure Lengend Snippet: D2. mdx vehicle-treated mice (Vehicle) had impairments when compared to DBA/2J vehicle-treated (Control) in both (A) Four-limb grip strength test and (B) Treadmill exhaustion test. D2. mdx mice treated with NDC-1171 did not improve in either behavior assessments. * p <0.05, ** p <0.01, and *** p <0.001.

Article Snippet: Male D2. mdx mice (n=18, strain #013141, D2.B10-Dmdmdx/J) and its background strain DBA/2J mice (Control) were obtained from Jackson Laboratory at 4 weeks of age (n=9).

Techniques: Control